Low-dose hydrocortisone in extremely preterm infants
نویسندگان
چکیده
منابع مشابه
Growth and neurodevelopmental outcomes after early low-dose hydrocortisone treatment in extremely low birth weight infants.
BACKGROUND Low cortisol concentrations in premature infants have been correlated with increased severity of illness, hypotension, mortality, and development of bronchopulmonary dysplasia. A total of 360 mechanically ventilated infants with a birth weight of 500 to 999 g were enrolled in a randomized, multicenter trial of prophylaxis of early adrenal insufficiency to prevent bronchopulmonary dys...
متن کاملNeurodevelopmental Outcomes of Extremely Preterm Infants Randomized to Stress Dose Hydrocortisone
OBJECTIVE To compare the effects of stress dose hydrocortisone therapy with placebo on survival without neurodevelopmental impairments in high-risk preterm infants. STUDY DESIGN We recruited 64 extremely low birth weight (birth weight ≤1000 g) infants between the ages of 10 and 21 postnatal days who were ventilator-dependent and at high-risk for bronchopulmonary dysplasia. Infants were random...
متن کاملPreterm Birth of Extremely Low Birth Weight Infants
Approximately 13% of births in the United States are preterm, defined as occurring before 37 weeks of gestation. This results in more than 540,000 infants a year born prematurely. In other words, one out of every 8 infants is born premature. Even more disturbing is that despite advances in neonatal and perinatal medicine, the incidence of prematurity has increased by 36% since the 1980’s. Over ...
متن کاملOutcome trajectories in extremely preterm infants.
OBJECTIVE Methods are required to predict prognosis with changes in clinical course. Death or neurodevelopmental impairment in extremely premature neonates can be predicted at birth/admission to the ICU by considering gender, antenatal steroids, multiple birth, birth weight, and gestational age. Predictions may be improved by using additional information available later during the clinical cour...
متن کاملChorioamnionitis and outcome in extremely preterm infants.
INTRODUCTION Chorioamnionitis is a risk factor for preterm delivery. Intrauterine infection leads to the fetal inflammatory response which is characterised by elevated cytokine levels. Chorioamnionitis is reported to cause accelerated but abnormal lung maturation, resulting in decreased incidence of respiratory distress syndrome (RDS) but increased chronic lung disease (CLD), and predisposes th...
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ژورنال
عنوان ژورنال: The Lancet
سال: 2016
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(16)31610-5